The Patriots, winners of five straight games, will travel to face the Colts on Sunday Night Football. Both teams enjoyed a Week 10 bye, so expect  an electric vibe when this game kicks off. The Patriots are coming off an impressive 43-21 home victory over the Broncos. Tom Brady threw for 333 yards and four touchdowns while Rob Gronkowski caught nine passes for 109 yards and a touchdown. Julian Edelman, Brandon LaFell and Shane Vereen also caught touchdown passes from Brady. New England’s defense gave up 481 yards of total offense, but won the turnover battle, two to one.

The Colts are coming off a convincing 40-24 road victory over the Giants on Monday Night Football. Andrew Luck threw for 354 yards and four touchdowns while Coby Fleener led the way with four catches for 77 yards a touchdown. Ahmad Bradshaw totaled 79 yards against his ex-team. TY Hilton and Reggie Wayne also scored while tight end Dwayne Allen hauled in a touchdown.

Brady has defeated Luck twice and has won four straight against Indianapolis, including a dominant 43-22 home victory last season in the playoffs. New England rushed for 234 yards and six touchdowns in the playoff win.

According to current NFL odds, the Colts opened as two-point home favorites against the Patriots. While this match-up favors the Colts since they’re playing at home, I like the Patriots in this match-up. I always take Brady and Belichick off a bye week especially in prime time. Take the Patriots today for your NFL picks!

Official Pick: New England Patriots +2