The Kansas City Royals have long been one of the whipping boys in baseball. In fact, the last time they were favored in a game against the New York Yankees came back in 2008, and that was the only game in which they were favored in this series since the 2005 season. Now, KC is expected to give the Bronx Bombers fits this weekend when the two meet at Kauffman Stadium, and New York could be in some trouble when you look at the pitching matchups that are on tap.

Friday’s clash pits RHP Phil Hughes against RHP Wade Davis. Davis has had a lousy career against the Yankees, but Hughes doesn’t have a win in his career against Kansas City either. Batters are knocking Hughes around to the tune of a .290 batting average this year, and the Royals have the bats to make him pay for leaving too many balls in the middle of the plate once again.

The best game for MLB picks in this series might be Saturday. The ageless LHP Andy Pettitte will challenge RHP James Shields in a game that the Royals will certainly be expected to win. Shields is only 2-2 on the season, but he is coming off of his best start in a Kansas City uniform when he allowed just two hits in eight scoreless innings against the Chicago White Sox.

On Sunday, this series wraps up with the two best pitchers in terms of ERA on these staffs squaring off. RHP Ervin Santana has been a pleasant surprise this year for the Royals with his 2.36 ERA, but he might be in some trouble in this game against New York. The Yankees are going to be throwing RHP Hiroki Kuroda, who has been the best pitcher on their staff with a 4-2 record and a 2.30 ERA to show for his work thus far this year.